liposomal structure

It has been reported that the composition and preparation methods of liposomes have a great influence on the basic properties of liposomes, such as polydispersity index, average particle size, drug loading efficiency, zeta potential, drug release behavior, and intracellular drug uptake. Therefore, it is necessary to understand the composition of liposomes.

Structure of Liposome

Liposomes are circular soft-matter vesicles formed by one or more bilayer membranes that separate aqueous media from each other. Phospholipid molecules are mainly composed of different polar head groups and two hydrophobic hydrocarbon chains. The polar group may be zwitterionic or negatively charged. Hydrocarbon chain molecules have different lengths and unsaturation.

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