HD In Vitro Disease Models

HDIn VitroDisease Models

With years of project experience, Creative Biolabs is a well-deserved expert in the field of neuroscience research. Based on an advanced technology platform and professional expert team, we are confident in offering customer-satisfied Huntington's disease (HD) in vitro models and related services to global clients.

Targets and Mutations Involved in HD

HD is caused by the expansion of a polymorphic trinucleotide repeat (CAG)n, encoding glutamine, located in exon 1, at the N-terminal coding region of the huntingtin (HTT) gene. The HTT gene spans 180 kb and contains 67 exons. The only disease-causing mutation identified in the HTT gene is the CAG repeat expansion.